. Consider Down syndrome. The MZ concordance for monozygotic twins is 89% and 7% for dizygotic...

. Consider Down syndrome. The MZ concordance for monozygotic twins is 89% and 7% for dizygotic twins. The numbers are significantly different. What is your conclusion? 5 points

What is the difference between broad and narrow sense heritability? 5 points

Solutions

Expert Solution

Monozygotic twins originte from a single ovum and sperm and it's further division in the uterus cause genetically and phenotypically same individual. So both of them have same genes. That means there is more chance of getting the same defect which is imprinted in their genome. In contrast, the dizygotic twins are products of different sperm and ovum. So they have lesser gene similarity as the different sperm and ovum may carries different genes. That means there is lesse chance of getting the same defect which is imprinted in their genome. Therefore, there will be significant difference in percentage of concordance between monozygotic and dizygotic twins in Down syndrome.

Broad sense heritability is defined as the fraction or ratio of total gentic variations to total phenotypic variations, whereas the narrow sense heritability is termed as the fraction or ratio of additive variations to total phenotypic variations.

gladiator answered 2 years ago

Next > < Previous

Related Solutions

There are two types of twins, monozygotic (identical) twins where the offspring are generated from the...

There are two types of twins, monozygotic (identical) twins where the offspring are generated from the unexpected splitting of the same fertilised egg, while dizygotic (fraternal) twins arise from independent fertilisations of two different eggs. Discuss the power of STR profiling in discriminating between monozygotic and dizygotic twins

The percentage of MZ twin pairs studied concordant for mental retardation is 97%, while the concordance...

The percentage of MZ twin pairs studied concordant for mental retardation is 97%, while the concordance of this trait in DZ twins is 37%. Assuming that both twins in each pair were raised together in the same environment, what do you conclude about the relative importance of genetic versus environmental factors in this trait?

one method to investigate gene-environment interaction is to study monozygotic twins. identify an example of a...

one method to investigate gene-environment interaction is to study monozygotic twins. identify an example of a twin study ised to examine the gene-environment interraction of a specific disease or condition. briefly sumarize the gene-environment interaction investigated the method and the result. what are other possible methods of studying gene-environment interaction as they relate to improving population health.

Research amniocentesis for Down Syndrome. What are the sensitivity and specificity for amniocentesis for Down Syndrome...

Research amniocentesis for Down Syndrome. What are the sensitivity and specificity for amniocentesis for Down Syndrome screening? Provide your reference/source.

in details what's is down syndrome ?

Bill and Betty have two children with Down syndrome. Bill’s brother has Down syndrome. His sister...

Bill and Betty have two children with Down syndrome. Bill’s brother has Down syndrome. His sister has two children with Down syndrome. On the basis of these observations, indicate which of the following statements are most likely correct and which are most likely incorrect. Explain your reasoning (Hint: Is the Down syndrome seen here likely familiar Down syndrome?) a. Bill has 47 chromosomes. b. Betty has 47 chromosomes. c. Bill and Betty’s children each have 47 chromosomes. d. Bill’s sister...

Minimum of 10 classroom modifications for students with Down Syndrome Concepts to consider: Classroom technology Curriculum...

Minimum of 10 classroom modifications for students with Down Syndrome Concepts to consider: Classroom technology Curriculum Classroom library Language Class discussions Physical classroom environment Social classroom environment Teaching methods Materials Learning activities and tasks Level of input or assistance from teacher.

Question