Question

In: Nursing

one method to investigate gene-environment interaction is to study monozygotic twins. identify an example of a...

one method to investigate gene-environment interaction is to study monozygotic twins. identify an example of a twin study ised to examine the gene-environment interraction of a specific disease or condition. briefly sumarize the gene-environment interaction investigated the method and the result. what are other possible methods of studying gene-environment interaction as they relate to improving population health.

Solutions

Expert Solution

Twin studies. Twins provide a number of ways to study gene-environment interaction. One such method is to study monozygotic twins reared apart (MZA). MZAs provide a unique opportunity to study the influence of different environments on identical genotypes.

For example, the child of an NBA player would probably be exposed to basketball from an early age. Such exposure might allow the child to realize his or her full genetic, athletic potential.

Gene-environment (G×E) interactions are worth studying for several reasons. Consideration of G×E interactions can improve the power for discovering genes that are involved in the etiology of disease primarily through an interaction effect with no marginal effect .

By examining G×E successes, it may be possible to improve the design of G×E studies for the future. In addition, several recent studies examined the use of polygenic risk scores, generated from common genetic variation, to assess the impact of environmental factors on individuals with low versus higher genetic risk


Related Solutions

Ecology One quantitative example of calculating interaction strength.
Ecology One quantitative example of calculating interaction strength.
What method can be used to identify the location of a gene on a chromosome? A....
What method can be used to identify the location of a gene on a chromosome? A. Fluorescent in situ hybridization (FISH) B. Fluorescent Immunohistochemistry (IHC) C. DNA fingerprinting D. Polymerase chain reaction (PCR)
Identify the four types and provide a unique example (one not in the slides/study guide) of...
Identify the four types and provide a unique example (one not in the slides/study guide) of each. For the upcoming year, Dorby, Inc. (which has an 8% required return) is expected to produce $10,000 operating income on $100,000 of invested assets by opening its flagship store. Dorby is considering expanding to a second location, which would require an additional $100,000 investment but would produce $9,000 additional operating income. What is the increase/decrease in return on investment (ROI) if the second...
A retrospective study of 159 pairs of twins was performed. The twin pairs each had one...
A retrospective study of 159 pairs of twins was performed. The twin pairs each had one male child and one female child. Their birth weights were studied to determine if the male twin was consistently heavier. The difference in weights was calculated by subtracting the female weight (in ounces) from the male weight (in ounces): d=xm-xf After looking at 159 pairs of twins, the study finds the 99% confidence interval for the mean difference of weights (in ounces) is: 2.4...
One example of a 1,3-diaxial interaction is when there are two axial methyl groups on the...
One example of a 1,3-diaxial interaction is when there are two axial methyl groups on the same side of a cyclohexane ring, called a syn pentane interaction. For cis-1,3-dimethylcyclohexane, the difference in energy between the two chair conformations is 5.3 kcal/mol. What is the energy value (in kcal/mol) of the syn pentane interaction? Show your work, i.e. how you arrived at your answer. You will need to draw both chair conformations of the molecule to properly answer the question. Chairs...
Which one of the following is a method of evaluating the external environment in which a...
Which one of the following is a method of evaluating the external environment in which a company operates that explicitly involves an assessment of the following: the threat of new entrants,) the threat of substitute products of services, the bargaining power of buyers, the bargaining power of suppliers, and the rivalry among existing firms? Select one: a. Mission and Vision Statement b. SWOT Analysis c. Five Forces Model d. Strategic Management
2.3.10 In Example 1.1, we looked at a study to investigate whether dolphins could communicate. In...
2.3.10 In Example 1.1, we looked at a study to investigate whether dolphins could communicate. In doing so, we tested whether Buzz, one of the dolphins, could push the correct button more than 50% of the time in the long run. a. Describe what a Type I error would be in this study. b. Describe what a Type II error would be in this study
in this example of complete dominance one gene determines the color of Martian's skin and a...
in this example of complete dominance one gene determines the color of Martian's skin and a second gene determines the color of Marian's blood. Albino skin is dominant over black skin and yellow blood is dominant over red blood. Determine the Genotypes and phenotypes from the cross below. Homozygous Albino/yellow x black/red F1? what if this was an example of incomplete dominance?
Identify one opportunity and one threat to Tesla in the general environment and briefly explain why....
Identify one opportunity and one threat to Tesla in the general environment and briefly explain why. Do you think the automobile industry is attractive or unattractive for incumbents? I know you want to explain with all five forces, but please give me two reasons related to any industry forces. Identify one strength and one weakness of Tesla and briefly explain why. Test the strength you found above with the VRIN framework, and conclude if it provides a competitive advantage, disadvantage,...
Identify a scientifically proven example of how nutrients in foods affect gene expression and disease development
Identify a scientifically proven example of how nutrients in foods affect gene expression and disease development
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT