What is the difference between a silent mutation, point mutation and a missense mutation?

Expert Solution

Ans: Point mutation: This type of mutation is caused because of a single nucleotide base change.

Following are the two possible reasons for the point mutations:

When one base is converted into another because of chemical modification.
When the wrong nucleotide is inserted during DNA replication.

There are 2 types of point mutation on the basis of nature of base change:

Transition: When purine ( adenine and guanine) is substituted by purine and pyrimidine with a pyrimidine. This is the most common type of point mutation.

Transversion: When purine is substituted with pyrimidine ( cytosine and thymine) or vice versa. This is the less common type of point mutation.

Missense mutation and silent mutation are the effects of point mutation.

Missense mutation: It is basically a point mutation in which change in single nucleotide will change the codon thus different amino acid will be coded.

Silent mutation: It is again a point mutation in which change in single nucleotide will change the codon but still the altered codon, code for the same amino acid so the effect of mutation is not observed that is why it is called a silent mutation.

The explanation to this is the wobble hypothesis according to which different codons may code the same amino acid.

please find the image below to understand this better.

gladiator answered 1 year ago

What is meant by a missense mutation? What is a nonsense mutation?

What is meant by a missense mutation?What is a nonsense mutation?What is a silent mutation?What is a frameshift mutation? Give an example of each type of mutation and discuss the effect on a protein product.

Describe each of the below mutations AND provide an example of each. Point mutation Missense mutation...

Describe each of the below mutations AND provide an example of each. Point mutation Missense mutation Nonsense mutation Silent mutation Transition Transversion Frameshift mutation

What is a codon? What is silent mutation?

Natural Selection! Explain using this words "pre-existing in a population" between silent, missense, nonsense, and frameshift...

Natural Selection! Explain using this words "pre-existing in a population" between silent, missense, nonsense, and frameshift mutations. Explain difference between silent, missense, nonsense, and frameshift mutation and include pre-existing variations in a population in the explanation?

What are the differences between synonymous and nonsynonymous mutations? What types of point mutations (frameshift, missense,...

What are the differences between synonymous and nonsynonymous mutations? What types of point mutations (frameshift, missense, nonsense, and silent) fall under synonymous and nonsynonymous? Are synonymous and nonsynonymous mutations cis or trans?

Explain the mechanism by which a missense mutation in the RAS gene that impairs the GTPase...

Explain the mechanism by which a missense mutation in the RAS gene that impairs the GTPase activity of the RAS protein promotes cancer cell division.

What is the difference between a suspicious data point and an extreme data point?

mutaions types: “synonymous” “nonsynonymous” mutations. “silent” “noisy”. “missense”, “nonsense”, and “sense” mutations. if mutations (and evolutionary...

mutaions types: “synonymous” “nonsynonymous” mutations. “silent” “noisy”. “missense”, “nonsense”, and “sense” mutations. if mutations (and evolutionary base substitutions) were truly random, then which of these categories of mutations would you expect to occur most often in protein coding sequences? Second most often?If you restricted your attention to the third codon position, then which category of mutation would you expect to occur most often? and why ?

1) It is almost impossible for a frameshift mutation to be silent. Explain why. 2) A...

1) It is almost impossible for a frameshift mutation to be silent. Explain why. 2) A person is exposed to a chemical mutagen that mutates the muscle cells in their arm in such a way that the muscle doesn't work. When that person has a child, do you expect that child to have the same mutation in their DNA? Why or why not?

5. What is the difference between the capillary melting point and true melting point?

Question