24. Erythropoietin (EPO) is a hormone produced by the kidneys and released in response to hypoxia...

24. Erythropoietin (EPO) is a hormone produced by the kidneys and released in response to hypoxia to promote the maturation of RBCs. During the 1980s, a human recombinant form of EPO (rHuEPO) became available. Explain the advantages and dangers of administering someone rHuEPO to increase oxygen-carrying capacity of blood.

25. a.Take your pulse.

b.Assuming that your SV is 70 ml and 1 ml of blood weighs 1g, calculate how long it would take your heart to pump your body weight in blood. (NB: 2.2 lbs = 1 kg).

Expert Solution

24. Erythropoietin is necessary for the production of red blood cells. By the action if the erythropoietin the redblood cells matures. The advantage of the recominant erythropoietin is the easy availability of the red blood cell. So that we can increase the red blood cell count. So in a situation like hypoxia we can treat patients with this and res blood cell Maturation will begin as soon as possible. We can treat patients in Anemia situation. If the erythropoietin production is not in the adequate level we can use this to increase the red blood cell count. The disadvantage is that. By this the hematocrit increases. The hematocrit is the redblood cell count per ml of blood. As the hematocrit increases the blood becomes more thicker and the resistance to flow increases. As a result of it the heart needs to pump more forcefully. It's much painful at the site of injection. Another one is the elevation of blood pressure. It may cause swelling and may lead to other associated situation like fever, dizziness etc.

25. a) normal pulse ranges in an adult from 60-100 in range. Ita usually seen in the range of 90. In athletes the pulse rate is less in the range of 40-60.

b) stroke volume is 70 ml. It'a told that 1ml of blood weighs 1 gram. So there is 1000 grams in 1kg. So for knowing the number of heartbeats to pump the time taken we should divide 1000/70= 14.3

Thus means the heart should beat 14.3 times to pump 1 kg blood. But its not a while number. In this case the heart should beat for 15 times to pump 1 kg of blood.

Sydney Mullin answered 1 year ago

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