In: Anatomy and Physiology
Discuss the structural organization of lipoprotein particles such as HDL, LDL or VLDL. List all of the biomolecules found in each and describe their function in the particle. How does their structure facilitate the function of the particles? What does each do?
Very low density lipoprotein(VLDL):
This contain high concentration of triglycerides(formed from FFA and glycerol) and moderate concentration of cholesterol and phospholipids. Its function is to transports triglycerides from liver to adipose tissue.
Low density lipoprotein(LDL):
Formed from intermediate density lipoprotein by the complete removal of triglycerides and contain only cholesterol and phospholipids. Intermediate density lipoprotein are formed from the very low density lipoprotein which is had very low portion of triglyceride than VLDL. The function is is to transport cholesterol and phospholids from liver to tissues and organs like heart.
High density lipoprotein(HDL):
It contain high concentration of proteins with low concentration of cholesterol and phospholipids. Except other it is synthesised in intestines others are synthesised in liver. It transport cholesterole and phospholipids from tissues and organs like heart back to liver. Due to the lower concentration of cholesterol it is called as good cholesterol.