In: Anatomy and Physiology
A type I diabetic is suffering from debilitating bursitis (inflammation of "bursa sacs") which makes moving their right arm almost insufferably painful. A physician diagnoses the bursitis and administers a hydrocortisone injection in the area of the bursa sacs to relive pain.
1. Why would injection of hydrocortisone provide pain relief?
2. Why might the patient's blood glucose levels remain elevated for several days following this injection?
1) Hydrocortisone is a corticosteroid which can be used as an injection for the management of the debilitating bursitis.
It is given by intra-articular route directly into the joint. Steroid medication injected into your bursa can help reduce the inflammation and alleviate the pain. The joints most often injected are the shoulder, elbow, knee, hand/wrist and hip.
The steroid down regulates immune system overactivity in the area and reduces inflammation. This in turn helps to relieve the pain and swelling.
2) Steroid therapy stimulate glucose production by the liver and inhibit peripheral glucose uptake. This resulting in insulin resistance. If the pancreas isn't able to make enough insulins or dose of insulin is not adjusted accordingly, this may will lead to hyperglycaemia.
Hence due to this reason, the patient blood glucose level remains elevated for several days following the injection.