the basic mechanisms by which enzymes increase the rates of chemical reactions can be classified into...

the basic mechanisms by which enzymes increase the rates of chemical reactions can be classified into four groups. What are they?

Expert Solution

1) Facilitation of proximity or propinquity effect - substrates are brought to close proximity at the active site of the enzyme

2) Covalent catalysis - A covalent bond is formed between the substrate and the enzyme (covalent bond is formed between the nucleophilic aminoacid side chain with the electrophilic center of the substrate) thus forming a reaction intermediate.

3) General Acid- Base catalysis - Acid- Base catalysis involves transfer of proton in the transition state

4) Strain, molecular distortion, shape change - strain in th bond of reactant and release of strain as the transition state gives rise to product

queen_honey_blossom answered 2 years ago

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