Question

In: Anatomy and Physiology

Find a digestive disease that you don't know about and write a report describing this disease....

Find a digestive disease that you don't know about and write a report describing this disease.

Make sure this report is in your own words.

Please add any personal comments/experiences.

Remember to cite where you got your information.

-Submit the report and post for discussion

Solutions

Expert Solution

HIRSCHSPRUNG'S DISEASE

- Congenital defect in colonic innervation, producing congenital aganglionic megacolon

- more common in males but severe in females

- 1:5000 live births

PATHOGENESIS:

• Failure of migration of neural crest cells into the bowel.

• Leads to absence of ganglion cells particularly nitric oxide releasing cells in bowel.

• Affected part of bowel is not able to relax.

• Proximal part of affected bowel gets dilated.

MORPHOLOGY:

Short Segment Hirschsprung's Disease: when part of large intestine is involved.

Long Segment Hirschsprung's Disease: When entire colon is involved.

MOST COMMON SITE: Rectum

CLINICAL FEATURES:

• Failure of passage of meconium.

• Abdominal Distension

• Constipation

• Dilation causes thinning if bowel wall which may lead to rupture (especially in colon).

DIAGNOSIS:

Confirmed by Rectal Suction Biopsy.

It reveals:

  1. Absence of ganglionic cells.
  2. Nerve fibres are hypertrophied.

Special stains are used.

• AchE: heavy staining (Normally, no staining)

• Calretinin: no staining (Normally, staining is present)

Reference: Robins Pathological Basis of Disease


Related Solutions

write a report about ( disease caused by Ascomycota powder mildews )..
write a report about ( disease caused by Ascomycota powder mildews )..
Given what you know about the current global pandemic, (and if you don't know much do...
Given what you know about the current global pandemic, (and if you don't know much do some news searches and reading), write a brief assessment (no more than a page) of the state of global governance in relation to Covid-19.
CAN SOMEONE WRITE THIS PAPER FOR ME PLEASE, I DON'T KNOW HOW TO DRIVE RECOMMENDATION REPORT,...
CAN SOMEONE WRITE THIS PAPER FOR ME PLEASE, I DON'T KNOW HOW TO DRIVE RECOMMENDATION REPORT, PLEASE HELP ME !!!!!! RECOMMENDATION REPORT ON HONDA ACCORD ( WORD 250)
in digestive system the main and accessory organs and their main function.? type don't write
in digestive system the main and accessory organs and their main function.? type don't write
Please write a few sentences describing a situation where you (or someone you know) has used...
Please write a few sentences describing a situation where you (or someone you know) has used their problem solving or agility skills to increase their human capital in order to get a better job or earn more income.
Sexually Transmitted Diseases (STDs) Write a report about ONE disease (not more than 1 page) about...
Sexually Transmitted Diseases (STDs) Write a report about ONE disease (not more than 1 page) about symptoms, treatments, & prevention techniques. Add your comments to help the discussion Please remember to cite your sources. Submit & post for discussion
Please Use your keyboard (Don't use handwriting) Thank you .. Write a report for:- Determine the...
Please Use your keyboard (Don't use handwriting) Thank you .. Write a report for:- Determine the relationship between those factors and how these factors can affect the adoption of e-HRM in the Palestinian companies.
Find a news or online article containing (apnea ) word. You don't have to write a...
Find a news or online article containing (apnea ) word. You don't have to write a paper but just a brief idea about the content of the article.
I have to write report about Application of Linear Algebra in Electronic Engineering. Let me know...
I have to write report about Application of Linear Algebra in Electronic Engineering. Let me know about the examples simply and variously as possible as you can.
Write a two-page executive report describing how information technology effects an enterprise familiar to you (your...
Write a two-page executive report describing how information technology effects an enterprise familiar to you (your workplace, a volunteer organization, a religious organization). What types of information systems do you find in your enterprise? Why is information technology important in this context? What information and knowledge is important to various stakeholders inside and outside the organization? How do information technology, information and knowledge currently add value to the enterprise? How could IT, information, and knowledge create value for this organization...
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT