Which sequence of events most accurately describes the reactive hyperemia response Select one: a. Flow occlusion,...

Which sequence of events most accurately describes the reactive hyperemia response

Select one:

a. Flow occlusion, increased accumulation of metabolites, arteriolar dilation

b. Decreased mean arterial pressure, increased accumulation of metabolites, arteriolar dilation

c. Increased mean arterial pressure, decreased accumulation of metabolites, arteriolar constriction

d. Increased mean arterial pressure, increased accumulation of metabolites, arteriolar dilation

e. Increased mean arterial pressure, increased accumulation of metabolites, arteriolar dilation

Solutions

Expert Solution

Answer) option A- flow occlusion, increased accumulation of metabolites and arteriolar dilation

Explanation -

REACTIVE HYPERAEMIA -

It is a increased blood flow to particular tissue or organ for a short period of time, when artery supplying it is occluded.

For example, occlusion of arterial blood supply to a limb for 5 minutes, the limb shows cutaneous hyperaemia associated with muscle hyperaemia (i.e muscle blood flow increases) due to -

1)local accumulation of metabolites (like adenosine, bradykinin, histamine) which causes dilatation of arterioles and pre-capillary sphincters.

2)increased release of nitrous oxide (which causes vasodilatation) secondary to local effect on hypoxia.

Since these metabolites are quickly dissipated by the flushing effect of the increased blood flow, therefore, reactive hyperaemia is of short duration.

Other options are incorrect -

Option B is incorrect -

As decreased mean arterial blood pressure causes decreased in blood flow, which can initiate reactive hyperaemia.

But, flow occlusion is more accurate and initiates morely reactive hyperaemia than decreased mean arterial blood pressure.

Option C is incorrect -

As increased mean arterial blood pressure causes more blood flow, decreased accumulation of metabolites and arterioal constriction causes do not increase blood flow.

Option D and E are incorrect -

As increased mean arterial blood pressure causes more blood flow, which do not initiate reactive hyperaemia.

Sydney Mullin answered 10 months ago

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