Question

1. Consider the endocrine system and hormones.

a)What are the three general chemical classes of hormone? ____________________________________________________________________________________ ____________________________________________________________________________________ ____________________________________________________________________________________
b)List the THREE physiological functions of the thyroid hormone. ____________________________________________________________________________________ ____________________________________________________________________________________ ____________________________________________________________________________________ ____________________________________________________________________________________ ____________________________________________________________________________________
c)How are thyroid hormones transported in the bloodstream? Why? Do the hormones enter the target cell directly? Describe the sequence of events when thyroid hormones bind to their receptors.

Answer 1

Question no 1

Three general class of hormones are

1. Lipid derived hormone that is also known as steroid hormones
2. Protein or peptides derived hormone
3. Amino acid derived hormone

These are the major hormones that are produced in body

Question no 2

Physiological functions of thyroid hormone

1. It acts upon all cells in our body and helps in maintaining BMR
2. It helps in maintainance of body temperature
3. The growth of bone is well regulated by deposition of calcium on bone
4. Helps in neural maturity

Question no 3

Thyroid hormone are secreted in to blood stream by the thyroid gland and in blood stream protein chaperones a specific type of chaperones help the thyroid hormone reach the targeted cell by binding with them

They need transport proteins as they are metabolically active when secreted into blood

Sequence of events

When thyroid hormone bind to receptors coactivator complex replace the co reppressor complex and the process of transcription occur in the cell with RNA polymerase 2. Ligand activated transcription factor helps in this response

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