Question

“1. What determines blood type? “

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“2. What type of blood antigens are expressed if a person is blood type AB negative? “

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“3. Why doesn’t a transfusion reaction occur the first time an Rh negative patient is exposed to Rh positive blood? “
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1. What surprised you about the anatomy of the sheep’s heart?

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2. Research diseases of the heart valves. How might a valvular insufficiency affect heart function? How would valvular stenosis (tightening or less ability to open easily) affect heart function?

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Answer 1

1.Blood type is Determined by the presence or absence of Antigens(A,B and Rh) on the surface of RBC .

Blood Type-

a.A +ve --Presence of Antigen A & Rh Antigen on RBC Surface.

b.A-Ve--Presence of Antigen A on RBC surface,no Rh Antigen.

c.B +ve--Presence of Antigen B & Rh Antigen on RBC Surface.

d.B -ve--Presence of Antigen B on RBC surface,no Rh Antigen.

e.AB +ve--Presence of Antigen A, B & Rh Antigen on RBC Surface.

f.AB -ve--Presence of Antigen A, B on RBC surface,no Rh Antigen.

g.O+ve-No A antigen,No B antigen But Rh antigen is present

h.O-ve-No A antigen,No B antigen & No Rh Antigen.

2.AB -ve--

Antigens Present:Antigen A, B

Antigen absent---Rh Antigen.

Antibody -No antibodies.

3.Rh +ve Blood means the Blood group contains Rh Antigen.

Rh -ve Blood Group means the Blood group donot contain Rh antigen.

But Both Rh +ve and Rh -ve Blood donot contain Anti Rh Antibodies Initially.So evenwhen an RH-ve blood recieves Rh +ve blood for the first time there is no transfusion reaction .But during the First time,Rh -ve blood recieving Rh +ve Blood---It starts producing Anti Rh antibodies in blood.So now Rh -ve blood contains Anti Rh Antibody--So if the Blood recieves Rh positive blood again ,There will be Transfusion reaction

An Rh -ve Blood donot contain Rh antigen