Question

Describe the regulation of filtration in the nephron (renal corpuscle) in response to blood pressure, nervous input, hormones, and Tubuloglomerular Feedback. (Be sure to compare activity at the afferent and efferent arterioles.)

Answer 1

The nephron is the microscopic and structural as well as functional unit of the kidney. These are formed of renal cortical as well as a renal tubule. The group of capillaries is known as the glomerulus. These are extended from the capsule and their primary function is to remove the waste product including the solid waste and excess water from the blood. The function of nephron is the basic functional unit of the kidney. This helps to regulate the water as well as soluble substances by the blood filtration as well as reabsorption.

The regulation of the filtration in the nephron with the response to the backpressure hormones, nervous input as well as tubuloglomerular feedback decrease the renal pressure. The construction of afferent arteriole also has a negative impact on vascular resistance which decreases the renal blood flow. This decrease the blood pressure from the constriction and decrease the glomerular filtration rate is observed. Constriction of the afferent arteriole involves the blood flow that decreased and enhance the filtration pressure. Regulation of filtration in the nephron takes place during the pressure gradient in the glomerulus. This manages the blood volume and blood pressure with the dilation of the afferent arteriole.