Question

In: Anatomy and Physiology

Which of the following is true regarding Langerhans cells and their activity? a) the Langerhans cell...

Which of the following is true regarding Langerhans cells and their activity?

a) the Langerhans cell is a specialized epithelial cell made of especially large amounts of keratin

b) they add pigment to keratinocytes in the stratum spinosum and this pigment acts to reduce the

chance of UV radiation damage to the keratinocyte nucleus

c) they are interfaced with underlying sensory neurons and enhance the detection of mechanical forces

applied to the skin

d) they sample the microflora found in the upper layers of the skin and can prepare the immune

system for potential invaders

e) they play a primary role in detecting UV radiation and directly influence melanocyte production of

melanin.

Solutions

Expert Solution

Which of the following is true regarding Langerhans cells and their activity?

a) The Langerhans cell is a specialized epithelial cell made of especially large amounts of keratin

b) They add pigment to keratinocytes in the stratum spinosum and this pigment acts to reduce the

chance of UV radiation damage to the keratinocyte nucleus

c) They are interfaced with underlying sensory neurons and enhance the detection of mechanical forces

applied to the skin

d) They sample the microflora found in the upper layers of the skin and can prepare the immune

system for potential invaders

e) They play a primary role in detecting UV radiation and directly influence melanocyte production of

melanin.

Ans:

a. The Langerhans cells do not contain keratin and are dendritic cells(antigen producing cells) of the skin.

b.They do not add pigment to keratinocytes.

c.They do interface with underlying sensory neurons.  

d. They sample the microflora found in the upper layers of the skin and can prepare the immune

system for potential invaders. Because Langerhans cells are dendritic cells of the skin.

e.They do not have any role in detecting UV radiation and melanocyte production.

Hence the answer is d.: They sample the microflora found in the upper layers of the skin and can prepare the immune system for potential invaders


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