In: Anatomy and Physiology
B
1
The lymphatic system, or lymphoid system, is an organ system in
vertebrates that is part of the circulatory system and the immune
system. It is made up of a large network of lymphatic vessels,
lymphatic or lymphoid organs, and lymphoid tissues. The vessels
carry a clear fluid called lymph
The lymphatic system consists of all lymphatic vessels and lymphoid organs
primary lymphoid organs-Bone marrow and the thymus,
secondary lymphatic organs -lymph nodes, the spleen, the tonsils
and other specialized tissues in the mucous membranes of the
bowel
Lymph and lymph vessels
The lymphatic system with its vessel network is – apart from the
circulatory system, with which it is closely connected – the most
important transport system in the human body.This clear to
yellow-tinted fluid is formed when blood plasma exits the capillary
blood vessels and fillls the small spaces (interstices) between and
around body tissues and cells before being collected through small
lymphatic vessels (lymph capillaries).
Lymph transports nutrients and oxygen for the cells as well as immune cells (such as lymphocytes). While circulating through the interstitial spaces of various tissues, lymph also picks up many of the body’s waste products and carbon dioxide. Apart from that, lymph transports fat from the intestines to the blood.
After having been collected by the lymph capillaries, lymph is transported through larger lymphatic vessels to the lymph nodes, where lymphocytes purge it before it is emptied into the large (subclavian) veins close to the heart, where it blends again with the blood.
Lymph nodes
The network of lymphatic vessels includes multiple interposed lymph
nodes, small lentil- or bean-sized organs. They serve as filter
stations for the lymph of a certain body region and contain
specials cells of the immune system.lymph nodes, which are commonly
found near the groin, armpits, neck, chest, and abdomen. Humans
have about 500–600 lymph nodes throughout the body
The spleen is an organ in the left upper abdomen. Its job is to
process old and damaged blood cells and microorganisms
The thymus is a gland located behind the breastbone (sternum). At
birth, the thymus is the largest organ of the lymphatic system. It
plays a vital role in building the immune system
.LARGER LYMPHATIC VESSELS, TRUNKS, AND DUCTS
The superficial and deep lymphatics eventually merge to form
larger lymphatic vessels known as lymphatic trunks. On the right
side of the body, the right sides of the head, thorax, and right
upper limb drain lymph fluid into the right subclavian vein via the
right lymphatic duct .On the left side of the body, the remaining
portions of the body drain into the larger thoracic duct, which
drains into the left subclavian vein. The thoracic duct itself
begins just beneath the diaphragm in the cisterna chyli, a sac-like
chamber that receives lymph from the lower abdomen, pelvis, and
lower limbs by way of the left and right lumbar trunks and the
intestinal trunk.
The overall drainage system of the body is asymmetrical.. The right
lymphatic duct receives lymph from only the upper right side of the
body. The lymph from the rest of the body enters the bloodstream
through the thoracic duct via all the remaining lymphatic trunks.
In general, lymphatic vessels of the subcutaneous tissues of the
skin, that is, the superficial lymphatics, follow the same routes
as veins, whereas the deep lymphatic vessels of the viscera
generally follow the paths of arteries.
2
Function of lymphatic
The lymphatic system is a linear network of lymphatic vessels and
secondary lymphoid organs. It is the site of many immune system
functions as well as its own functions.
It is responsible for the removal of interstitial fluid from
tissues into lymph fluid, which is filtered and brought back into
the bloodstream through the subclavian veins near the heart.
Edema accumulates in tissues during inflammation or when lymph
drainage is impaired.
It absorbs and transports fatty acids and fats as chylomicrons from
the digestive system.
It transports white blood cells and dendritic cells to lymph nodes
where adaptive immune responses are often triggered.
Tumors can spread through lymphatic transport.
3
lymphatics in maintaining homeostasis
The lymphatic system helps maintain fluid balance in the body by collecting excess fluid and particulate matter from tissues and depositing them in the bloodstream.The lymphatic system can be thought of as a drainage system needed because, as blood circulates through the body, blood plasma leaks into tissues through the thin walls of the capillaries. The portion of blood plasma that escapes is called interstitial or extracellular fluid, and it contains oxygen, glucose, amino acids, and other nutrients needed by tissue cells. Although most of this fluid seeps immediately back into the bloodstream, a percentage of it, along with the particulate matter, is left behind. The lymphatic system removes this fluid and these materials from tissues, returning them via the lymphatic vessels to the bloodstream, and thus prevents a fluid imbalance that would result in the organism’s death.
4
There is no heart-like pump for the lymphatic system. Instead, as
you breathe and move your muscles, the lymph continuously gets
pushed toward the heart from the outer reaches of your body. (It’s
very much like how blood depleted of oxygen moves back toward your
heart through the veins.) First the lymph moves out of the
lymphatic capillaries and into larger lymphatic collector vessels.
These vessels have muscular walls and one-way valves that keep the
lymph moving in the right direction. Many of the lymphatic vessels
sit just under the surface of your skin.There is no heart-like pump
for the lymphatic system. Instead, as you breathe and move your
muscles, the lymph continuously gets pushed toward the heart from
the outer reaches of your body. (It’s very much like how blood
depleted of oxygen moves back toward your heart through the veins.)
First the lymph moves out of the lymphatic capillaries and into
larger lymphatic collector vessels. These vessels .during
inspiration there is a drop in intrathoracic pressure and an
increase in intra-abdominal pressure as the diaphragm pushes down,
with consequent movement of lymph from the abdominal to the
thoracic cavity. During expiration they suggested that the increase
in intrathoracic pressure causes lymph to be expelled through the
thoracic duct into the upper thorax
5
The lymphatic system plays a vital role as one of the organ systems
of the body. This system functions with the digestive system to
absorb dietary lipids , which enter lymphatic vessels rather than
blood vessels for transport. It also acts with the cardiovascular
system to control the body's fluid balance.A substantial part of
the gastrointestinal tract is occupied by lymphoid tissue, which
can be divided into three sectors. The first is represented by the
pharyngeal tonsils, the appendix, and the large aggregates of
nodules known as Peyer patches located at intervals throughout the
small intestine. The second sector includes the lymphocytes and
plasma cells that populate the basement membrane (lamina propria)
of the small intestine, the area of loose connective tissue above
the supporting tissue of the mucosal lining extending into the
villi. The third sector comprises lymphocytes that lie between the
epithelial cells in the mucosa. The interaction between these cells
of the lymphatic system and the threatening agent is the basis of
defense in the gastrointestinal tract.