Answer
: The mitotic cell division was first explained by
W. Flemming in 1882. It consists of four
sub-stages:
- Prophase : Each of
the available chromosome becomes individual
long thread like structure when the
chromatin network begins to coil. They will have
two chromatids held together by
centromere. The nucleus and the nuclear
membrane gradually disappears in this
stage.
- Metaphase : The
metaphase stage begin when the nucleus and the nuclear
membrane disappears. The chromosomes also becomes
shorter by coiling. All the centromeres
arrange themselves in the equator forming metaphase plate
or equatorial plate. The chromosomes become
visible and both the chromatids in each chromosome
face the opposite poles. In this phase the spindle fibres
are seen arising out of the centromeres. Now the
centromeres are ready to divide and the
two chromatids would seperate.
- Anaphase : The
anaphase stage begins once the centromere divides.
The spindle fibres contract and the chromosomes
assume V or J or I shaped structures. They are due
to the variable position of the centromeres.
- Telophase : The
chromosome begin to uncoil,
elongate and become invisible.
The nuclear membrane and the nucleolus reappear.
By the end, two daughter nuclei are formed, one at
each pole.
Cytokinesis
: Cytokinesis means division of the
cytoplasm. A cell wall is formed around
the daughter nuclei. The golgi bodies helps in
generating the cell membrane. Hence, by the end of the
mitosis two identical daughter cells are formed.
Note: Division of
cytoplasm is cytokinesis whereas the division of nucleus is
Karyokinesis.