In: Biology
What are osteoblasts? What are osteoclasts?
Osteoblasts are bone forming cells. They are cells with single nucleus that synthesize bone. They also come from the bone marrow and related to structural cells. They work in teams to build bone. They produce newbone called osteoid which is made of bone collagen and other protein. Then they control calcium and mineral deposition. They are found on the surface of the newbone. When the team of osteoblasts has finished filling in a cavity, the cells become flat and line the surface of the bone. These old osteoblasts are called Lining cells. They regulate passage of calcium into and out of the bone, and they respond to hormones by making special proteins that activate osteoclasts.
Osteoclasts are larger cells that dissolve the bone. They come from the bone marrow and related to white blood cells. They are formed from two or more cells which fused together so they have more than one nucleus. They are found on surface of bone mineral next to the dissolving bone.