Researchers found a crude odds ratio of 1.8 in a case-control study.

Researchers found a crude odds ratio of 1.8 in a case-control study. They stratified their analysis within levels of a binary potential confounder and found an odds ratio of 1.2 in one level of the confounder and an odds ratio of 2.8 in the other level of the confounder.

A. Do you think they should present the adjusted odds ratio in the report of their results?

B. Why or why not?

Solutions

Expert Solution

Odds ratio =

Probability of an event/1- Probability of the event

So odds ratio is defined as the probability of an event happening, divided by the probability of an event not happening. So a higher odds ratio means greater chances of the event happening.

Note: Odds ratio> 1, means increased chances of an event occuring

Odds ratio<1, means decreased chances of the event occuring.

A) Here in the case control study, the odds ratio is already > 1, ie 1.8

But in stratified analysis we find odds ratio of 1.2 in one level and 2.8 in the other level.

So yes we should show this stratified analysis in the report to show greater level of detail.

B) This analysis shows us that the probability of occurrence of one event is relatively higher (with odds ratio 2.8), and then it's lower (closer to 1) for the other variable. So the overall is high because 2.8

orchestra answered 1 year ago

Next > < Previous

Related Solutions

In a hypothetical case-control study, researchers are interested in exploring the activities and behaviors of individuals...

In a hypothetical case-control study, researchers are interested in exploring the activities and behaviors of individuals at Northwestern University that may be associated with increased risk for testing positive for COVID-19. a. What inclusion and exclusion criteria would you use? Why? b. Define who is considered a case. How might you identify cases? c. Carefully define who is in the control group. How might you accurately identify control individuals? d. For the case-control study, how would you collect information on...

A. Researchers conducted a case control study to identify the association between alcohol consumption and esophageal...

A. Researchers conducted a case control study to identify the association between alcohol consumption and esophageal cancer among men. They enrolled 187 men with esophageal cancer and 715 men without esophageal cancer. The men were asked about their regular alcohol consumption and the men were categorized as either drinking ≥80 g/day (exposed) or <80 g/day (unexposed). Among the men with esophageal cancer, 92 drank ≥80 g of alcohol per day; 177 of the men without esophageal cancer drank ≥80 g...

Tasmanian researchers conducted a case –control study to investigate the effect of dietary fat intake on...

Tasmanian researchers conducted a case –control study to investigate the effect of dietary fat intake on skin cancer. They hypothesised that people whose dietary fat intake is low will be more susceptible to skin cancer. The study compared 500 cases of melanoma with 500 controls who were randomly selected from the state’s electoral roll. The researchers categorised the dietary fat intake into three categories High, Moderate and Low. They found that among skin cancer patients 150 were classified at the...

Tasmanian researchers conducted a case –control study to investigate the effect of dietary fat intake on...

Researchers at Johns Hopkins decide to use a case control study design to explore the association...

Researchers at Johns Hopkins decide to use a case control study design to explore the association between women with breast cancer and DDT exposure. They interview women that have breast cancer undergoing chemo at the Johns Hopkins Hospital in Baltimore in 2014 and then take blood samples to test for DDT exposure. They also enroll a group of controls (without breast cancer) in the study based on patient lists at the hospital and also test them for DDT exposure. They...

In another case –control study researchers investigated cleft lip with or without cleft palate by smoking...

In another case –control study researchers investigated cleft lip with or without cleft palate by smoking status in those participants who reported consuming folic acid supplements. In this sub-group there were 42 cases of cleft lip with or without cleft palate and 55 controls who were current smokers; and there were 72 cases of cleft lip with or without cleft palate and 190 controls who were non-smokers.” (a) “Construct a 2x2 table with columns and rows headings and calculate an...

What is a nested case control study? What is the difference between a nested case control...

What is a nested case control study? What is the difference between a nested case control study and a case control study?

construct a persuasive argument for the value (conditional probability, odds, odds ratio, etc.) that, intuitively, makes...

construct a persuasive argument for the value (conditional probability, odds, odds ratio, etc.) that, intuitively, makes the most sense for you to report as a result to your audience. Be sure to provide a specific rationale for your choice

If a calculated odds ratio is 1, it indicates: a. The outcome is the same in...

If a calculated odds ratio is 1, it indicates: a. The outcome is the same in both groups b. There is not difference between groups c. The null hypothesis should be retained d. All of the above

If a calculated odds ratio is 1, it indicates: a. The outcome is the same in...

If a calculated odds ratio is 1, it indicates: a. The outcome is the same in both groups b. There is not difference between groups c. The null hypothesis should be retained d. All of the above

Subjects