Question

A few weeks after someone has recovered from coronavirus infection that caused COVID-19, you would expect to find T cell receptors to ind to fragments of viral COVID-19 proteins in the:

a. plasma b. hematocrit c. buffy coat d. globin e. formed elements

Answer 1

There are two types of T lymphocytes i.e. CD4+ and CD8+ T, they play an important role in the defense against pathogenic microorganisms (bacteria and Virus). Since CD4+ T cells trigger B cells so that they will produce virus-specific antibodies, while as CD8+ T cells can directly kill cells infected by virus. Since the presentation and processing of viral coat proteins is done by T-cells and it is expected that remnants of viral protein will be present with T cell receptor mix. If we are collecting the blood from a recently coronavirus recovered individual and allow it to centrifuge, then we will be able to see the three layers i.e. bottom layer of red blood cells (hematocrit), a top most layer of plasma/serum and an intermediate smaller pale layer known as buffy coat. This smaller layer of buffy coat contains white blood cells (including T cells, B cells etc) and platelets.

Therefore, based on the above explanation, the correct option is c. buffy coat