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In: Biology

what is the last step of lipid biosynthesis is it the patheay for phosphoglyceride

what is the last step of lipid biosynthesis is it the patheay for phosphoglyceride

Solutions

Expert Solution

Last step of lipid biosynthesis is the 3 addition methyl group on carbon atoms 4 & 14 are removed to produce zymosterol.

Then double bond migrates from 8-9 position to 5-6 position ,when desmosterol is formed. Desmosterol is present in fetal brain. It is absent in adult brain.

Finally double bind in side chain (between C-24 &C-25 ) is reduced by NADPH when cholesterol is formed.

Yes it is the pathway for phosphoglyceride because phosphatidate is a triglyceride & phosphoglycerides are derived from phosphatidate by the formation of an ester bond between the phosphate group of phosphatidate and the hydroxyl group of one of several alcohols.


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