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Quaternary Structure Quaternary structure represents the three-dimensional (3D) structure of one functional protein. 25. The 3D...

Quaternary Structure

Quaternary structure represents the three-dimensional (3D) structure of one functional protein.

25. The 3D quaternary structure is facilitated by interactions between which portions of the polypeptide chain? (Select one)

  1. Backbone atoms

  2. Side chains/R groups

26. List the different types of interactions that can occur at the level of quaternary protein structure.

  1. Covalent bonds

  2. Interactions between individual amino acid R units that are near to each other in the linear

  3. sequence

  4. interactions of individual amino acid R groups between different chains

  5. Individual amino acid R units that are separated from each other by a large distance along the linear sequence of amino acids.

27. How many polypeptide chains are present in the Quaternary structure of a protein?

28. When proteins have multiple polypeptide chains, what are the individual polypeptide chains called?

29. Find an example of a functional protein that is composed of multiple polypeptide chains (other than the example given in class). Provide the name of the protein below.

30. Draw a representation of the protein named above (in question 29). Be sure to decipher the different subunits.

Solutions

Expert Solution

25. Backbone atoms

Quaternary structure is held together by noncovalent bonds between complementary surface hydrophobic and hydrophilic regions on the polypeptide subunits. Additionally, acidic and basic side chains can form salt linkages.

26. Individual amino acid R units that are separated from each other by a large distance along the linear sequence of amino acids.

Quaternary structure is held together by noncovalent bonds between complementary surface hydrophobic and hydrophilic regions on the polypeptide subunits. Additionally, acidic and basic side chains can form salt linkages.

27. 4 polypeptide chains are present n the Quaternary structure of a protein.

28.  some proteins are made up of multiple polypeptide chains, also known as subunits.

29. Haemoglobin, pyruvate dehydrogenase, fatty acid synthase

30.


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