Question

In: Anatomy and Physiology

What is the role of acetylcholinesterase at a synapse? It stimulates the post-synaptic neuron. It breaks...

What is the role of acetylcholinesterase at a synapse?

It stimulates the post-synaptic neuron.

It breaks down acetylcholine.

It releases calcium ions.

All apply.

Solutions

Expert Solution

Correct option.

2nd option.

It breaks down the acetylcholine.

After release of the acetylcholine is hydrolyzed by the enzyme acetylcholine esterase to choline and Acetate. It clear the acetylcholine from the synopses.

Incorrect options:

1st option.

It not stimulate the post synoptic neuron.

The neurotransmitters like acetylcholine stimulate the post synaptic neuron.

Calcium ions stimulate the movement of synaptic vesicles towards the member where they fise with plasma membrane and release thire neurotransmitters in the synaptic cleft by exocytosis. The neurotransmitters bind the specific recptors, presant on the post synoptic membrane. Acetylcholine is the most common neurotransmitter.

3rd option:

Acetylcholine esterase not release the calcium ions.

The axon terminals contain vesicles filled with neurotransmitters. When an impulse ( action potential) arrives at axon terminal. It depolarize the membrane opening of voltage gated calcium channels ,it cause the release the calcium ions.


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