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In: Biology

list the modifications involved in processing mRNA

list the modifications involved in processing mRNA

Solutions

Expert Solution

1. 5'-capping- This is the first step of the processing of mRNA in this process 7-methylguanosine is added to the 5' end of the nacent mRNA. Cap functions as -protection if mRNA from degradation, transportation of mRNA from nucleus to cytoplasm and binding of ribosome with mRNA.

2. Polyadenylation- In this process upto 250 adenosines are added by the enzymenpoly-A polymerase to the 3'end of the mRNA called poly- A tail. It functions as- export of mature mRNA from the nucleus. affects stability of mRNA and serves as a recongnition signal for the translatonal factors.

3. Intron splicing- The process of excising the sequences in RNA that corresponds to introns and joining of sequences corresponding to exons is called RNA splicing. Splicing occures because eukaryotic RNA consists of introns (noncoding) and exons (coding) regions.

4. RNA editing- This process is widespread in eukaryotics, and defined as changing the nucleotide sequences of RNA; so that a mature RNA differs from that encoded by the genomic sequence.


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