In: Anatomy and Physiology
1. to which protein does calcium bind in order to expose the active sites
2. list the four connective tissue structure associated with skeletal muscle
The skeletal muscle contraction is activated when acetylcholine is released by motor neuro into the neuromuscular junction under the influence of action potential. This acetylcholine bind to the nicotinic receptors in the motor end plate and produce a muscle action potential. This muscle action potential opens the Ca2+ releasing channels in the sarcoplasmic reticulum membrane and influx of Ca2+ into the sarcoplasm occur. These calcium binds to the troponin (a regulatory protein) and expose myosin (a structural protein) binding sites on action
1. Calcium binds to troponin (a structural protein present in the thin filament) and expose the active site (myosin binding site on actin)
2. Connective tissues protect and support the body organs. This also cover and protect skeletal muscle in various level of anatomical structure. The following are four connective structure associated with skeletal muscle
Endomysium: A layer of dense irregular connective tissue covers entire skeletal muscle (outermost layer)
Perimysium: Dense irregular connective tissue layer that encircle a group of muscle fibers (usually 10 to 100 fibers) and form fascicle (seperate muscle bundles).
Epimysium: It is areolar connective tissue layer encircle individual muscle fibers
Tendon: It a cordlike extension of dense regular connective tissue that connects muscle tissue to bone