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In: Biology

what are the most common bacteria cause neonatal meningitis and recovered from CSF ?

what are the most common bacteria cause neonatal meningitis and recovered from CSF ?

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Expert Solution

The most common causes of neonatal meningitis is bacterial infection of the blood, known as bacteremia (specifically group B streptococci (Streptococcus agalactiae), Escherichia coli, and Listeria monocytogenes). Although there is a low mortality rate in developed countries, there is a 50% prevalence rate of neurodevelopmental disabilities after meningitis caused by E. coli and Streptococcus agalactiae, and a 79% prevalence after meningitis caused by Gram-negative rods other than E. coli. Delayed treatment of neonatal meningitis may cause cerebral palsy, blindness, deafness, seizure disorders, and learning deficiencies.

The treatment of CSF leaks depends on the location of the leak. Leaks into the sinuses can usually be repaired through minimally invasive, endoscopic procedures. CSF leaks from the ear typically require open surgery.

Endoscopic repair of CSF rhinorrhea (drainage from the nose)

In this procedure, the physician accesses the leak through the patient’s nose, avoiding an external incision. After the location of the leak has been precisely located, small pieces of tissue from the nasal lining are placed on the site.

The success rate of this minimally invasive procedure is 90 to 95 percent; it carries far less risk than an open approach. But as with any surgical procedure, endoscopic sinus surgery does have certain risks, such as:

  • Bleeding, scarring, or infection
  • Change in smell or taste
  • Injury to the eye (loss of vision, temporary or prolonged double vision, or eye tearing)
  • Infection spreading to the brain, resulting in meningitis

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