Why does hemoglobin have a lower affinity for the first oxygen molecule it binds than it...

Why does hemoglobin have a lower affinity for the first oxygen molecule it binds than it does for the binding additional molecules?

Expert Solution

queen_honey_blossom answered 2 years ago

Which molecule binds oxygen better, myglobin or hemoglobin? Why are these relative affinities important in oxygen...

Which molecule binds oxygen better, myglobin or hemoglobin? Why are these relative affinities important in oxygen delivery to the body?

1. Hemoglobin binds to and has a much higher affinity for carbon monoxide (CO) than for...

1. Hemoglobin binds to and has a much higher affinity for carbon monoxide (CO) than for oxygen. CO is colorless and odorless and can be produced in homes heated by natural gas; victims usually do not realize they are being poisoned and often die in their sleep. Describe the likely changes in a CO poisoning victim. 2. You are a physiologist on a space flight to a distant planet. You discover intelligent humanoid aliens inhabiting the planet, and they willingly...

Which of the following will decrease the affinity of oxygen for hemoglobin at low oxygen partial...

Which of the following will decrease the affinity of oxygen for hemoglobin at low oxygen partial pressures and shift the oxyhemoglobin saturation curve to the right, resulting in increased oxygen unloading for active tissues? Select one: a. high CO2 b. low H+ c. low temperature d. high hemoglobin levels e. low CO2

Explain, how following conditions influence affinity of hemoglobin and myoglobin to oxygen: a) falling of pH...

Explain, how following conditions influence affinity of hemoglobin and myoglobin to oxygen: a) falling of pH in blood plasma from pH=7.4 to pH=7.2. b) falling of partial pressure of CO2 from 6 kPa to 2 kPa c) Increase in BPG level from 5 mM to 8 mM.

Why does H2S have a lower boiling point than H2Se? Why does H2O have a much...

Why does H2S have a lower boiling point than H2Se? Why does H2O have a much higher boiling point than H2S?

Why is oxygen not sp2 hybrdized on the CO2 molecule and why does it remain primarily...

Why is oxygen not sp2 hybrdized on the CO2 molecule and why does it remain primarily unhybridized with only p orbitals sticking out?

Adult hemoglobin (iron-containing protein) can carry up to four oxygen molecules per hemoglobin molecule, with the...

Adult hemoglobin (iron-containing protein) can carry up to four oxygen molecules per hemoglobin molecule, with the addition of oxygen proceeding in a step-wise fashion. For the third step, the value of the equilibrium constant is Keq=5.86 x 10^-4 although the reaction has a (delta Hº) value of -2.9 kj/mol (Remember that the system is not at room temperature). Heme-Fe^2+ -(O2)2 + O2 <----> Heme-Fe^2+ -(O2)3 Keq=5.86 x 10^-4 (a) calculate delta Gº for this process. (b)From the information provided, calculate...

a. Why does hemoglobin bind so much more readily to a second and third molecule of...

a. Why does hemoglobin bind so much more readily to a second and third molecule of oxygen than to the first? b. why is the deoxyhemoglobin and the oxyhemoglobin so intensely colored? c. How is carbon dioxide really removed from the cells (it does not bind to the hemoglobin)?

1. Explain how the oxygen affinity of hemoglobin can affect the followings: 1.1 Amino acid substitutions...

1. Explain how the oxygen affinity of hemoglobin can affect the followings: 1.1 Amino acid substitutions that disrupt H-bonding at the α,β-interface 1.2 Substitution L136P, which destabilizes the subunit interactions 1.3 Disease in which the individual has increased levels of fetal hemoglobin 1.4 Consumption of methanol that causes a drop in blood pH (Metabolic acidosis)

2222You have discovered a unique molecule which binds only to anthrax spores and when it does,...

2222You have discovered a unique molecule which binds only to anthrax spores and when it does, fluoresces at 650 nm. Please design an inexpensive microchip detector for rapidly screening for the presence of anthrax. Describe details of your feasibility study. Assume lab feasibility of your design is successful; describe your work flow to translate this technology for public use. (Your answers should be clearly described Use schematics diagrams if needed)

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