Question

In: Anatomy and Physiology

A friend of yours needs bypass surgery. She does not want to get blood from a...

A friend of yours needs bypass surgery. She does not want to get blood from a blood blank and asks you to call up her friends and ask them to donate blood. Her blood type is A-

You find out that 4 have blood type O+; 5 have blood type A+; 1 has blood type O-; 1 has blood type B-; 1 has blood type AB-

You will ask the friends with blood type/s _______________________ to donate blood. Why? Your answer must include an explanation about antigens and antibodies.

Solutions

Expert Solution

Out of all these,only blood group "O-ve" can be given to the patient.

Explanation: Compatibility of donor's and recipient's blood can be decided by ABO blood grouping. Surface antigens of antigen A and B is present on membrane of RBC.Antibodies for these antigens are present in the plasma.

In an individual, antibodies against the same antigen is never present.Compatibility of donor and recipient is decided by the presence of antigen and antibodies in their blood.

If antigen and antibody (for that particular antigen) are mixed,agglutination reaction or Antigen-antibody reactions takes place and will cause hemolysis of RBC.

Also if a person is Rh-ve, we cannot give Rh +ve blood group because the person will start producing antibodies against Rh antigen and clumping or agglutination will take place.

*in this question, we have to give the patient a blood group which has Rh-.Now,as the patient is having Antigen A, and antibody B,we have to give a blood group which is having no antigen.Therefore O- is correct.

Sydney Mullin answered 1 year ago
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