Question

In: Biology

If a donor unit contains anti-D which was somehow missed by the antibody screen, would this...

If a donor unit contains anti-D which was somehow missed by the antibody screen, would this be detected by the major crossmatch if the recipient is Rh positive? Why or why not?

Solutions

Expert Solution

Based on presence of Rh factor, blood groups are of 2 types. Rh +ve and Rh -ve and blood groups are A,B,AB And O which may be +ve or -ve based on the presence of Rh factor.

O-ve blood group is safe for everyone (universal donor)

In case of emergencies, when there is no time to test, O-ve blood is used.

PEOPLE WITH RH +VE BLOOD CAN RECEIVE RH +VE OR RH -VE BLOOD.

If a person has Rh -ve blood they should only receive Rh -ve blood.

Cross matching is a step in the series of steps in blood compatability test which is done before blood transfusion to determine if donor's blood is compatable with recepient's blood. This is also done during organ transplantation.

In Major cross match, recepient's serum is tested against donor packed cells to determine if the recepient has preformed antibidies against any antigen on donor's cells.

If a donor unit contains anti-D which was missed by the antibody screen, this can be detected by the major crossmatch even if the recipient is Rh positive based on the antobodies present in the sample.


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