Describe the role of V(D)J recombination in anti- body diversification. Explain why nonhomologous end joining is...

Describe the role of V(D)J recombination in anti- body diversification. Explain why nonhomologous end joining is an advantageous mechanism to repair the double-stranded DNA breaks (fusion of the coding segments after the hairpins are hydrolyzed) in the V(D)J recombination pathway.

Expert Solution

inhumans Million and billion of different antibodies are produced from few genes. these conditions become possible due to the Di combinations and different jeans are there in RNA and proteins. these recommendations are known as VDJ recombination.

VDJ are part of the proteins and helpful in the formation of multiple diversity in antibody structure.

hair pin formation is a structural linear chain of nuclear tide formation for the synthesis of antibodies with various different sequence.

Here, in the diagram the loop form between oh and phosphate is a hairpin loop in the DNA.

the recombination occurs at different levels at the level of DNA RNA and protein.

gladiator answered 1 year ago

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