Non-homologous end joining (NHEJ) and Homologous recombination repair (HRR) are important DNA repair mechanisms in the...

Non-homologous end joining (NHEJ) and Homologous recombination repair (HRR) are important DNA repair mechanisms in the mammals. With diagrams, explain how the repairs are carried out in NHEJ and HRR. Are they completely independent pathways? Justify your answer with specific examples.

Expert Solution

gladiator answered 1 year ago

Briefly explain how both non-homologous end joining (NHEJ) and homology directed repair (HDR) repair mechanisms normally...

Briefly explain how both non-homologous end joining (NHEJ) and homology directed repair (HDR) repair mechanisms normally work in the cell, and which types of CRISPR induced mutations can be created by each.

1. Homologous recombination in meiosis has the main purpose of_____ a. Dna repair b. creating new...

1. Homologous recombination in meiosis has the main purpose of_____ a. Dna repair b. creating new chromosomes c.sealing double stranded breaks - i think the answer is creating new chromosomes since it lines up in pairs and swaps segments of dna 2. The invading end is usually a _______ a. 3' end b. 5' end c. both - I think it is 3' end because I couldnt find 5' end in text book 3. The extension of the paired region...

Compare and contrast homologous recombination and site specific recombination. Address their principles, molecular mechanisms, and physiological...

Compare and contrast homologous recombination and site specific recombination. Address their principles, molecular mechanisms, and physiological functions

DNA shuffling is a method for in vitro homologous recombination of pools of selected mutant genes...

DNA shuffling is a method for in vitro homologous recombination of pools of selected mutant genes by random fragmentation and polymerase chain reaction (PCR) reassembly. In our class, we went through a paper describing the evolution of four cephalosporinase from various species. The paper showed that a single cycle of shuffling yielded 8-fold improvements from the four separately evolved genes, versus a 270- to 540-fold improvement from the four genes shuffled together (so called family shuffling). Discuss how this result...

What is homologous recombination? What is site-directed recombination?

1) What are double-strand breaks, and how does homologous recombination repair them? 2) What types of...

1) What are double-strand breaks, and how does homologous recombination repair them? 2) What types of genes are transcribed by RNA polymerase I, II, III? Be sure that it is clear which genes are for which polymerase. Please only answer in sentences no pictures, etc.

answer the following regarding DNA repair mechanisms What is "direct repair"? Give a couple of examples...

answer the following regarding DNA repair mechanisms What is "direct repair"? Give a couple of examples of the enzymes involved. Which one requires light and what kind of mutation does it repair? Which one repairs bases with alkyl groups attached? Which base is involved? What is “nucleotide-excision repair”? What kinds of mutations can it repair? In prokaryotes, what four key proteins are involved and how did they get their names? What two enzymes are involved? What is “mismatch repair”? What...

Compare and contrast the three major mechanisms of DNA repair using a VENN Diagram. Mechanisms: Proofreading...

Compare and contrast the three major mechanisms of DNA repair using a VENN Diagram. Mechanisms: Proofreading by DNA Polymerase III during replication, Mismatch Repair, and Nucleotide Excision Repair

Describe the role of V(D)J recombination in anti- body diversification. Explain why nonhomologous end joining is...

Describe the role of V(D)J recombination in anti- body diversification. Explain why nonhomologous end joining is an advantageous mechanism to repair the double-stranded DNA breaks (fusion of the coding segments after the hairpins are hydrolyzed) in the V(D)J recombination pathway.

What is homologous recombination? What is site-directed recombination?Compare and contrast the two processes. Address their principles,...

What is homologous recombination? What is site-directed recombination?Compare and contrast the two processes. Address their principles, molecular mechanisms, and physiological functions.

Question