Question

In: Biology

Two diseases that are associated with specific HLA types. Report your findings below; each description should...

Two diseases that are associated with specific HLA types. Report your findings below; each description should include which HLA antigen is associated and the specific effect on the patient?

Expert Solution

There are number of diseases which are associated with HLA the diaseases are both infectious and non infectious in nature.Eg graves disease,type 1 diabetes,multiple sclerosis,Rheumatoid arthrities,systematic lupus erythematosus.

Graves diasease

It is an autoimmune thyroid disease which result in overproduction of thyroid hormone.In this enlargment of thyroid occur.

This disease is associated with HLA class II DR3 type.The amino acid (arginine) substitution at position 74 of beta 1 chain DR of HLA DR3 incraese the susceptibility to graves diasease.

SYMPTOMS

Many of signs and symptopms of graves diasease overlap with hyperthyroidism.

>anxiety and irrritability

>insomnia

>hand triemor

>enlargment of thyroid gland (goiter)

>buldging eyes

>Rapid and irregular heart beat

SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

It is the autoimmune diasease in which autoantibodies develops against self nuclear and cytoplasmic antigens of body.

HLA class II are associated with this diasease

haplotypes bearing the DRB1*03:01, DQB1*02:01 and the DRB1*15:01, DQB1*06:02 alleles 65 %people bearing these haplotypes are suffered with this diasease.

It is proved that DRB1*03:01 allele carries a higher risk than the DRB1*15:01.Homozygous individuals is highest risk of SLE.

SYMPTOMS

>chest pain during respiration

>skin rash -butterfly rash in face

>joint pain

>oral ulcer

>fatique

>senstivity to sunlight

gladiator answered 1 year ago

What are the associated pro's and con's with healthcare services advertising and report your findings in...

What are the associated pro's and con's with healthcare services advertising and report your findings in depth. Then, communicate where you stand on the issue and justify your position and why.

1. Write two case definitions for each of the following diseases. Be VERY specific. Cite your...

1. Write two case definitions for each of the following diseases. Be VERY specific. Cite your sources. Which definition do you think will identify more cases and why? Influenza i.Case definition #1: ii.Source for #1 iii.Case definition #2: iv.Source for #2: v.Which definition do you think will identify more cases and why? Measles i.Case definition #1: ii.Source for #1 iii.Case definition #2: iv.Source for #2: v.Which definition do you think will identify more cases and why? Chikungunya i.Case definition #1:...

Describe the below diseases, bacteria associated and associated characteristics -Psittacosis -Pneumonia (Be sure to include the...

Describe the below diseases, bacteria associated and associated characteristics -Psittacosis -Pneumonia (Be sure to include the predominant etiological agent) -Q fever -Tuberculosis -Whooping cough If applicable, identify the causative agent(s) reservoir for pathogen (e.g. human, animal, environment) mode of transmission diagnostic indicators (e.g. Ghon complexes, spherules, fried-egg appearance on media, thick-walled cysts, etc…)

Below are descriptions of different steps in the immune response. Each description has an associated letter....

Below are descriptions of different steps in the immune response. Each description has an associated letter. Use the letters to answer the questions below matching each question with the best answer. Note, only use each letter once in answering the questions. A. Phagocytosis of the pathogen B. Memory B cells recognizing an antigen and activating a secondary immune response C. Release of interferons from an infected cell that activates apoptosis of nearby cells D. Antigen-presenting macrophage interacts with a helper...

Describe the lines of defense associated with the immune system. Your description should include: Four examples...

Describe the lines of defense associated with the immune system. Your description should include: Four examples of anatomical barriers Three of the primary mediators of inflammation Names and brief descriptions of the four features that the specific immune system exhibits Name the two cell types known as lymphocytes and name their origin and maturation locations. Then, indicate how the cell mediated response (T cells) is activated.

Using the table below, describe the types of budgets. In your description, include: • The objective...

Using the table below, describe the types of budgets. In your description, include: • The objective of the budget • How the budget assists an organization in managing its financial activities • What types of data need to be included in that specific budget. Types of Budget Description Cash Flow Operating Sales Static Financial

Moving average and weighed moving average. Report your findings

A:Standard Precautions Your research should include what types of diseases/diagnoses it is used for, what type...

A:Standard Precautions Your research should include what types of diseases/diagnoses it is used for, what type of precautions should be used and how to notify working personnel/visitors of set precaution I found Disease Measles also called Rubeola talk about this disease ? 1) Disease: Measles 2) Pathophysiology of Disease: (How is it transferred to the patient) 3) What type of precautions should we be used for this type of disease: (PPE? equipment) 4) What regulatory agency in the United States...

Blood types and the markers associated with each blood types

Continuing with the scenario from your product overview, report your findings and recommendations to the stakeholders...

Continuing with the scenario from your product overview, report your findings and recommendations to the stakeholders of your company. Your job is to help the company launch a new pet food line. The food line will be for both cats and dogs, and the company is excited because the product is made of all natural ingredients. You will need to make some key strategic recommendations about how to launch and promote this new product line. Create a presentation to share...