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In: Biology

For the new virus SARS-Cov-2, carefully describe the steps leading to the initiation of a primary...

For the new virus SARS-Cov-2, carefully describe the steps leading to the initiation of a primary adaptive immune response upon infection and the effector mechanisms produced to clear the infection in terms of receptors and effector molecules specific to the type of pathogen.

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Expert Solution


SARS-CoV-2 pathogenesis is triggered by viral infection, and amplified by dysfunctional immune responses. Severe disease takes two major forms: acute respiratory distress syndrome (ARDS) where lung damage occurs to an extent where the patient is unable to get sufficient oxygenation, and sepsis where uncontrolled inflammation due an immunological phenomenon called the " Cytokine storm" leads to septic shock and systemic dysfunction of multiple organs.


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