The new corona virus (SARS-CoV-2) has become a major health
concern to humans. Based on what...
The new corona virus (SARS-CoV-2) has become a major health
concern to humans. Based on what you learned about the HIV case
study, what can we learn from DNA sequence data of the novel
virus?
In relation with the SARS-CoV-2 (the new Corona virus) pandemic,
UK government followed “Herd immunity strategy”; based on what you
studied about the concept of herd immunity, define the concept ,
explain how the concept might be applicable in real life and give
your opinion about the strategy. (100 – 150 words)
For the new virus SARS-Cov-2, carefully describe the steps
leading to the initiation of a primary adaptive immune response
upon infection and the effector mechanisms produced to clear the
infection in terms of receptors and effector molecules specific to
the type of pathogen.
What is the Spike protein found in the SARS-CoV-2 virus?
Describe the structure of the S protein (quaternary, tertiary,
secondary and primary protein layers). Also highlight key domains
and features of the structure of the S-protein that are important
for its function.
The current pandemic is caused by the virus SARS-CoV-2. It is
predicted to have an R0 value between 2 and 2.5. What factors would
cause the R0 value for SARS-CoV-2 to increase or decrease between
different populations of people?
The “novel coronavirus” (SARS-CoV-2) that is causing much
concern this winter/spring is a member of the family
Coronaviridae. Describe the structure, and the
nature of the genetic material, of the
Coronaviridae.
Various experiments have shown that the SARS CoV-2 is
an RNA virus that enter the human cells through a transmembrane
receptor called angiotensin converting enzyme 2 (ACE2). Polymerase
chain reaction (PCR) and genome sequencing have been cardinal in
both diagnosis and research into the COVID-19 pandemic. Currently,
DNA sequences of both SARS CoV-2 virus and susceptible human hosts
are available. As a student of molecular biology and biotechnology,
use the above information to answer the following
questions.
9.In the study...
Various experiments have shown that the SARS CoV-2 is
an RNA virus that enter the human cells through a transmembrane
receptor called angiotensin converting enzyme 2 (ACE2). Polymerase
chain reaction (PCR) and genome sequencing have been cardinal in
both diagnosis and research into the COVID-19 pandemic. Currently,
DNA sequences of both SARS CoV-2 virus and susceptible human hosts
are available. As a student of molecular biology and biotechnology,
use the above information to answer the following
questions.
6.
Given the...
1) The spike protein on the surface of SARS-CoV-2 virus
particles interacts with the ACE2 protein on our cells to initiate
infection. The protein, TMPRSS2, then cleaves the spike protein
allowing the virus to enter the cell. This leads to both cell death
via pyroptosis and a widespread inflammatory response that damages
the lung infrastructure.
Scientists have identified a mutation in the TMPRSS2 gene that
reduces viral entry in mice. Infected cells with the
tmprss2 mutation make TMPRSS2 protein that...
You are a researcher studying the coronavirus (SARS-CoV-2). You
want to know whether the virus frequently jumps from one mammal
species to another or whether different strains remain specific to
certain hosts over evolutionary time. How could you use
phylogenetic methods to test this?
Why does this matter for medical doctors and the world to know
?