Question

Please answer this in a chart about the following test with the information needed as stated in the problem.

1.Create a chart to organize serological tests listed below that use antigens and their corresponding antibodies. Create columns for the name of the tests, the category of the tests, the description of the tests and examples of the tests under the categories.

-Precipitation Tests

-Turbidimetric and Nephelometric Tests

-Agglutination Tests

-Neutralization Tests

-The Complement Fixation

-TestLabeled Antibody

-TestsPoint-of-Care Testing

Answer 1

Name of the test	Type of the test	Description of the test	Examples
Precipitation Tests	Serological test including antigen-antibody	When antigen and antibody react with each other in sufficient amount, then antigen-antibody complex is make precipitate in the solution.	Immunodiffusion
-Turbidimetric and Nephelometric Tests	Serological test including antigen-antibody	When antigen and antibody combines with each other, they will precipitate and look cloudy. In this situation this cloudy appearance can be measured by turbidimetry and nephelometry. Light is passed through the complex to measure the concentration.	Detection of plasma proteins like IgA, IgM level.
Agglutination Tests	Serological test including antigen-antibody	Cells like erythrocyte or bacterial cells has antigens on their cell surface. When antibody corresponding to their particular antigen react, they form a cloud like appearance. This test is called agglutination.	Blood group test
Neutralization Tests	Serological test including antigen-antibody	Neutralization test involves antigen-antibody reaction. In this test the biological effects which are produced by virus or toxins can be neutralized by antibodies which are homologous to it.	Virus Neutralization Tests.
The Complement Fixation	Serological test including antigen-antibody	In this test, a patient serum is examined for the presence of specific antibody. Complement is a component of serum which causes lysis of cells which are coated with antibody. Thus if Serological test including antigen-antibody a particular antibody is present in the serum, the corresponding antigen can make complex and activates the complement system. Now, when complement is attached with antigen-antibody complex it can not bind anymore with the indicator reagent which is used to identify the presence of the complex.	Used in diagnosis of viral infection.
TestLabeled Antibody	Serological test including antigen-antibody ( Immunofluroscence)	In labelled antibody is used to detect the presence of corresponding antigen directly on the sample. A particular antibody is labelled with fluorescence and this labelled antibody then use to capture the presence of corresponding antigen.	Detection of bacteria
TestsPoint-of-Care Testing	Rapid Serological test	Point of care testing is performed outside the laboratory. They are performed where patient is and these type of tests are given quick results.	Glucose test kit Pregnancy test kit