Somatic Recombination: A) Is a dynamic process of large-scale genomic relocation that occurs in many somatic...

Somatic Recombination:

A) Is a dynamic process of large-scale genomic relocation that occurs in many somatic cells.

B) Is a dynamic process which generates a large variety of antibodies.

C) In the immune system involves three different loci in humans.

D) All of these answers are true.

Expert Solution

D. All of the given answers are true.

Somatic recombination is a large scale genomic relocation that occurs in many somatic cells. This is the process by which a large number of DNA sequences or genes are translocated along the genome. Recombination occurring between sister chromatids of homologous chromosomes are considered as somatic recombination and are observed in all the somatic cells. The process is achieved by deletions or translocations of genes.

It is a dynamic process that generates a large variety of antibodies. Somatic recombination occurs in developing lymphocytes during their maturation. By achieving this recombination a large number of antibodies that can recognize a wide range of antigens are produced. V(D)J gene segments are altered by the action of recombinases producing different genetic recombinants contributing to antibody diversity.

Somatic recombination occurs in immune system of humans that involves three different loci. The varying constant and variable chains of an antibody are produced by the recombination events occurring in three loci, they are immunoglobulin heavy chain locus, lambda locus and kappa locus.

gladiator answered 2 years ago

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