Question

What are the key differences between glycolysis in the liver and in muscle? Why is this important for the function of those different types of cells/tissues within the human body?

Answer 1

Glycolysis : Glycolysis is the metabolic reaction which produces two molecules of ATP through the conversion of glucose into pyruvate, water, and NADH in the absence of oxygen. The glucose for glycolysis can be provided by the blood supply, but is more often converted from glycogen in the muscle fibers

Just like in skeletal muscle cells, there are three enzymes that are used to regulate glycolysis in the liver. Phosphofructokinase contains two allosteric inhibitors, ATP and citrate. When any of these two molecules rises in concentration, they will create a negative feedback loop that inhibits the enzyme.

Glycolysis must be closely regulated in the cells of our body. Therefore the primary purpose of glycolysis in skeletal muscle tissue is to generate ATP molecules. There are three points of regulation within glycolysis and these points are all enzymes that catalyze irreversible steps in the glycolytic pathway.

Human body tissue makes up organs and other body parts. There are four main types of tissue: muscle, epithelial, connective and nervous. Each is made of specialized cells that are grouped together according to structure and function. Muscle is found throughout the body and even includes organs such as the heart.