Protein Code: 1CJY which is HUMAN CYTOSOLIC PHOSPHOLIPASE A2. Please go in depth about what the...

Protein Code: 1CJY which is HUMAN CYTOSOLIC PHOSPHOLIPASE A2.

Please go in depth about what the structural features are of the protein? (primary, secondary, tertiary, quaternary)

Expert Solution

PROTEIN CODE: 1CJY - HUMAN CYTOSOLIC PHOSPHOLIPASE A2.

WHAT IS THE STRUCTURAL FEATURES ARE OF THE PROTEIN?

On going through Rcb database or uniprot database we get the structure features of this pholipase can be of

It is of secondary structure it's helix,turn,strand can be in position of

KEY FEATURES	POSITION
Beta strand	18-29
Helix	34-39
Beta strand	44-49
Beta strand	51-54
Beta strand	57-60
Beta strand	70-79
Beta strand	86-93
Beta strand	96-98
Beta strand	100-108
Helix	109-111
Beta strand	117-124
Turn	125-127
Beta strand	128-137
Beta strand	143-146
Helix	152-177
Helix	179-181
Beta strand	190-194
Helix	198-214
Helix	218-220
Beta strand	221-226
Helix	228-239
Turn	241-245
Helix	248-260
Helix	263-266
Helix	269-284
Helix	291-304
Helix	305-307
Helix	313-318
Turn	319-321
Beta strand	326-333
Helix	341-343
Beta strand	344-349
Beta strand	354-356
Turn	357-360
Beta strand	361-363
Helix	365-367
Beta strand	370-373
Beta strand	376-379
Helix	386-393
Helix	396-399
Helix	401-404
Helix	417-423
Helix	426-429
Helix	463-476
Beta strand	488-490
Turn	492-495
Beta strand	543-548
Helix	550-552
Helix	558-561
Helix	564-566
Beta strand	570-575
Helix	588-599
Helix	611-615
Beta strand	619-623
Beta strand	636-641
Helix	646-648
Beta strand	650-652
Helix	660-666
Beta strand	670-672
Helix	687-702
Helix	705-718

This table shows the position in which secondary structure reveals.

STRUCTURE OF CYTOSOLIC PHOSPHOLIPASE:Cytosolic phospholipase A2s has molecular weight, 85 kDa belong to group VI.Unlike the majority of PLA2s with the catalytic histidine,these enzymes have serine residue in the active site.Intracellular phospholipases are calcium- sensitive enzymes. They are large ( 700 a.a.)molecules containing specific C2 domain responsible for the protein transport to the plasma membrane.

gladiator answered 1 year ago

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