In: Biology
1. It is easier to modified unicellular organism because it is a type of targeted approach for genetic modification. It involves the insertion of foreign gene directly into the unicellular organism.
But in case of multicellular organism, we have to insert the gene into the germline cell which will then undergo meiosis to form gamete. Gamete from two different parents will fertilize to give rise to a zygote. Now we do not know which gamete contains the following gene and which do not.
The process of selection of transformed is easier in case of unicellular as compared to multicellular. The transformation of multicellular organism is difficult and time consuming.
2. It is better to take an organism which grows and reproduces quickly. It is because if the organism grows and produces quickly, then it will be easier for us to select for the transformed organism against non transformed organism. If the organism is not yet transform, then we can perform the experiment again. But if the organism will take too much of time to grow and reproduce, then it will be very time consuming to perform the whole experiment of transformation.
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