In: Biology
What is meant by the term "cotranslational disassembly". To what sorts of viruses does it apply? How does it help to explain the "life-cycle" of these viruses?
1) Use examples from ssRNA viruses to show how some viruses' genome organization and replication strategy conform to the principle of genetic economy and explain why your chosen examples are appropriate..
Co-translational disassembly is a one of the mechanism of virus replication. T For some virus, having RNA as genetic material, co-translational disassembly helps in the uncoating of virus.
In this co-translational disassembly , the virus structure is relaxed mostly either through chelation of divalent cations or a pH of approximate 7 and ribosome of the host cell is situated at the 5? end of the genome of virus, that is an mRNA. The ribosome move along with the mRNA, that resulted in the deciphering the genetic information of virus along with the, uncoating of viral coat protein subunits.
It occurs in the tobacco mosaic virus, some isometric viruses. It occur in those virus, where genetic material is DNA
It helps in the life cycle of virus in the following way:
As the co-translational disassembly helps in the replication of the virus in the host, it is an important for the virus life cycle. Since, virus complete its life cycle in the host, its replication within the host is necessary and this is accomplished by Co-translational disassembly.