What has to occur for an enzyme to catalyze a reaction? Select all correct. A. The...

What has to occur for an enzyme to catalyze a reaction? Select all correct.

A.	The enzyme and substrate cannot interact with each other
B.	The enzyme and substrate have to undergo a chemical with each other
C.	The enzyme and an inhibitor have to come into contact at the active site
D.	The enzyme needs to become denatured prior to contact
E.	The enzyme and substrate have to undergo temporary non-covalent interactions with each other
F.	The enzyme and substrate have to come into contact at the active site

Expert Solution

Ans) The correct options are "E and F"

Substrate binds to the active site of an enzyme to form Enzyme-substrate complex which is then converted into product. They may form hydrogen bonds,hydrophobic interactions or transient non-covalent interactions. Every enzyme has its optimum activity at particular pH,Temperature etc above or below which its activity decreases.Denatured enzymes cannot catalyze chemical reaction efficiently because with elevated temperature the bonds are disturbed and thus low reaction efficiency. Inhibitors can bind covalently,reversibly or irreversibly to change the conformation of the enzyme so that the enzyme cannot bind to the substrate and thus no chemical reaction is catalyzed when inhibitor is present.

gladiator answered 2 years ago

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