In: Biology
1)Cystic fibrosis an autosomal recessive disorder caused by a single gene, affects the lungs, the pancreas, the digestive system, and other organs, resulting in symptoms ranging from breathing difficulties to recurrent infections. Which of the following terms best describes this?
A)incomplete dominance
B)multiple alleles
C)codominance
D)epistasis
E)pleiotropy
2)What is one function of a signal peptide during peptide translation?
A)to terminate translation of the messenger RNA
B)to signal the initiation of transcription
C)to bind RNA polymerase to DNA and initiate transcription
D)to direct an mRNA molecule into the cisternal space of ER
E)to translocate polypeptide across the ER membrane
3)Which of the following statements correctly describes the function of a signal peptide?
A)It helps target a protein to the ER.
B)It signals the initiation of transcription.
C)It terminates translation of messenger RNA.
D)It directs an mRNA molecule into the cisternal space of the ER.
1) incomplete dominance- in the heterozygotes shows intermediate phenotype compared to both homozygotes
multiple alleles- there are more than two alleles at a locus in a population.
co-dominance- both alleles are expressed in the heterozygous condition.
epistasis- one locus determines whether alleles at the second locus is expressed or not.
pleiotropy- one gene affects multiple phenotypes.
here cystic fibrosis is controlled by a single gene, but it affects multiple phenotypes so the answer is e) pleiotropy.
2) The signal peptide is required to translocate the protein to its destination within the cell.
for example, ER signal sequence, once it is translated, Signal recognition particle binds to it and targets the mRNA-signal-peptide -ribosome complex to translocon in the ER membrane, so that the protein can be translated into the ER lumen or inserted into the ER membrane.
E) to translocate polypeptide across the ER membrane
3) The signal peptide is required to translocate the protein to its destination within the cell.
for example, ER signal sequence, once it is translated, Signal recognition particle binds to it and targets the mRNA-signal-peptide -ribosome complex to translocon in the ER membrane, so that the protein can be translated into the ER lumen or inserted into the ER membrane.
A)It helps target a protein to the ER.