Question

PLNIP is a gene found in the human genome that is responsible for the production of lipase. Lipase is a type of protein enzyme that digests lipids.

Some events in the creation of lipase

1. mRNA is brought to the ribosome

2. RNA polymerase copies PLNIP

3. elongation of polypeptide chain occurs

4. tRNA reads the codon UAA

The sequence in which the events numbered above occur when lipase is produced are ____, ____, ____, and ____.

(Record all four digits of your answer in the numerical response section of your answer key)

Answer 1

Answer:

PLNIP gene codes for lipase and is present in the human genome. The question asked above is more of knowing about the central dogma of Molecular Biology very nicely.

The answer to the above question is:

The sequence in which the events numbered above occur when lipase is produced are

2. RNA polymerase copies PLNIP gene (Transcription)

1. mRNA is brought to the ribosome. ( Before the process of translation)

3. Elongation of a polypeptide chain occurs. ( Translation)

4. tRNA reads the codon UAA.

Here, firstly the RNA polymerase will copy the gene PLNIP into mRNA which is transcription. Then, functional mRNA will bind to the small subunit of the ribosome and later to a large subunit to begin the process of translation. Then tRNA will bring respective amino acids to codons by complementarity to the codon of mRNA. After adding amino acids, the polypeptide chain elongates. You might be wondering why 4. doesn't come before 3. but UAA doesn't code for any amino acid which means that it is a stop codon that specifies the termination of the translation process and polypeptide will be formed after undergoing through secondary and tertiary folding and transformations will form a functional protein lipase.

Note: Till now there are no tRNAs identified which will show complementarity to stop codon sequence, or in other words, empty tRNA are not seen to be carried to the stop codon sequence as it won't specify for any amino acid.

I hope this answer helps you!

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