Why EIIA and EIIBC are clustered with seemingly unrelated genes?

Expert Solution

Enzyme II A (EIIA) and Enzyme II BC (EIIBC) are both components of the phophostransferase system, working majorly in the carbohydrate metabolism/ transportation across membranes, including that of lactose, galactose, melibiose and mannose. These are linked components and appear in bacteria under the same operon (eg. Lac operon). EIIA is coded by lac F and EIIBC by lac E.

Studies have been carried on these enzymes by creating mutants for the particular enzyme and evaluating effect on growth and metabolism. In such an attempt, it was found that the functions of both these enzymes are the same. However, it was believed that both of them have role in galactose transport. But, it was later seen by a mutant under strong GUS promoter that both these enzymes have lac T antitermination activity in lac operon, but lac F was found to be a strong inducer of lac operon. Moreover, unphosphorylated EIIBC also helped in the galactose transport in small proportions.

Also, it has been seen that EIIA is equally important in nitrogen phosphotransferase system.

It is thus clear that the two enzymes have same functions, but may have additional functions too, for which they are coded by different genes.

gladiator answered 1 year ago

Are all genes turned on all the time in all cells? Why or why not? (write...

Are all genes turned on all the time in all cells? Why or why not? (write down).

Assuming that all unrelated acquisitions are at arm's length, why is the accurate valuation of goodwill...

Assuming that all unrelated acquisitions are at arm's length, why is the accurate valuation of goodwill so important? Why should you be concerned about it? Do you think that FAS 142 helped provide accuracy to the valuation of goodwill?

Given: bicoid genes are maternal genes; kruppel genes are gap genes, even-skipped genes are pair rule...

Given: bicoid genes are maternal genes; kruppel genes are gap genes, even-skipped genes are pair rule genes, gooseberry genes are gooseberry. Predict the effect of scenarios below on expression levels of each of these gene classes in the embryo described (will expression increase, decrease, or be unaffected?) and explain the reason for your prediction. a. a fly embryo has a mutation that blocks expression of the kruppel gene b. a fly embryo has a mutation that blocks expression of the...

vWhat is the function of the MHC antigens? Why are the genes that encode these antigens...

vWhat is the function of the MHC antigens? Why are the genes that encode these antigens so variable

substitutes, complements, or unrelated

Please describe the different ways that eukaryotic genes are regulated and why it is important that...

Please describe the different ways that eukaryotic genes are regulated and why it is important that we have such an incredible number of ways to regulate the amount of protein expressed in a cell. This is a 10 point question, please take your time to answer it with ample evidence and examples.

9. Most of the genes in the human genome code for enzymes. Why? What are the...

9. Most of the genes in the human genome code for enzymes. Why? What are the functions of enzymes?

Please can you explain that why in a spurious regression the coefficients between unrelated variables appear...

Please can you explain that why in a spurious regression the coefficients between unrelated variables appear very significant.

One of the most seemingly obvious things in all of our experiences is that the Earth...

One of the most seemingly obvious things in all of our experiences is that the Earth is still and the Sun moves across the sky. And yet, we are told by science, that the Earth is moving not the Sun. How is it that scientists are so certain about this? This is not a quiz! How do you think this certainty came about?

Explain in depth "unrelated diversification".

Question