Question

In: Biology

How is co-expression induced?

How is co-expression induced?

Solutions

Expert Solution

Co-expression refers to the expression of multiple genes regulated by the same transcriptional control. These could either be the functionally related genes involved in a common biological process or the ones that are interdependent to elicit a particular response in the cell.

For instance - Operon system - An operon consists of multiple genes that have a coordinated expression in reponse to the regulations imposed by the trancription machinery.

So, how the regulation in this co-expression system is imposed?

This control is elicited in different ways:

1. When product of one gene acts as an inducer for the transcriptional activation of another. For eg- In many pigmented flowers, expression of one gene yields a product that induces another to trancribe so that the pigments are formed.

2. Expression from a single promotor- In operons, cluster of genes involved in a single pathway are regulated by a single promoter. for eg- Lac operon.

3. Epigenetic regulations - Certain epigenetic modifications on gene promotors simultaneously activate genes involved in a particular biological activity. for eg- acetylation by histone acetyltransferases (HATs) is one such modification.


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