In: Biology
1. Which of the following groups of allosteric effectors are all sensors of an energy poor status in the cell?
Group of answer choices
a.cAMP, CoASH, ADP
b.ATP, NADH, acetyl CoA
2. Which one of the following statements about gluconeogenesis in mammals is false?
a.It consists entirely of the reactions of glycolysis, operating in the reverse direction.
b.It requires metabolic energy (ATP or GTP).
c. It can use amino acids as starting material.
d. The pathway includes the liver enzyme glucose-6-phosphatase.
3. Which of the following is true of mammalian glycogen synthase?
It catalyzes addition of (α1 ⟶⟶ 4) linked glucose residues to the nonreducing end of a glycogen chain.
PKA activation of glycogen synthase requires phosphorylation of one or more amino acids.
The enzyme binds F2,6 bisphosphate (F26BP).
cAMP is an allosteric effector that binds and inhibits glycogen synthase.
c.AMP, NAD+, CoASH
d. Acetyl CoA, AMP, NAD+
4. If a cell is actively fluxing only phases I (oxidative) and II (isomerase) of the pentose phosphate pathway, which of the following statement most accurately describes the physiological status of the cell from the information given?
The cell is in an energy-poor status.
The cell is at the point in its cell cycle where DNA replication is highest.
The cell is under oxidative stress and needs high level of glucose.
The cell is producing heat through uncoupled electron flow.
5.
Which of the following is true about F26BP (fructose-2,6bisphosphate)?
Its level is regulated by glucagon in the mammalian liver.
It is synthesized and broken down by a bifunctional enzyme.
It is not an intermediate in any metabolic pathway.
All statements about F26BP are true.