(1) State one piece of evidence that supported the vesicular transport model of the Golgi. State...

(1) State one piece of evidence that supported the vesicular transport model of the Golgi. State one piece of evidence that seems to show that the cisternal maturation model may be more correct than was once thought. State one function of the Signal Recognition Particle.

(2) _____The lysosomal enzymes have a tag that directs them to the lysosome. These enzymes are sorted into their appropriate vesicles in which of the following?

A. RER

B. cis Golgi

C. trans Golgi

D. SER

Solutions

Expert Solution

Q1- radiolabelled lipids of cis cisterna when forms vesicles for transport substances from cis to tras glogi, budding and fusion of vesicle transfers radiolabelled lipids to trans lipids small patch due to fusion of small lipids. it indicate that there is vesicular transport of substances.its all by receptor mediated.

Cisternal maturation is true because cis middle and trans cisterna are formed due to vesicular transport of proteins same time secretory pathway and prorein modification carried out with the formation of cisterna.and in retrograde trasnport from endocytosis it will maintain sizes of cisterna due to reverse direction of vesicular transport.

Q2 answer is Cis glogi where mannose 6 phosphate added as tag to destine protein into lysosome.

ER just synthesizes proteins.

ER sorted tags and destined for specifix location.

Cis golgi has enzyme to tag protein.

Trans golgi just bud off with receptor to fuse with lysosome.

gladiator answered 1 year ago

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