List and describe the general phases in animal virus multiplication. Contrast the multiplication of an enveloped...

List and describe the general phases in animal virus multiplication. Contrast the multiplication of an enveloped virus with that of a naked virus.

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Expert Solution

The phases of animal virus multiplication are:

Adsorption- Binding of virus to specific molecule on host cell

Penetration- Genome enters host cell

Uncoating- Viral nucleic acid is released from capsid

Synthesis- Viral components are produced

Assembly-New viral particles are constructed

Release-Assembled viruses are released by budding (exocytosis) or cell lysis.

Enveloped viruses may enter differently than naked viruses. Some viruses inject their nucleic acid, whereas others must also ensure that a virus-associated RNA or DNA polymerase enters the cell. Some naked viruses undergo a major change in capsid structure on adsorption to plasma membrane, so that their nucleic acids are released into the cytoplasm, some enveloped viruses engulfed by receptor-mediated endocytosis to form coated vesicles, which fuse with lysosomes. Lysosomal enzymes may help with uncoating. Naked virions usually released by host cell lysis, enveloped viruses bud out through cell membrane.

gladiator answered 1 year ago

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