Question

In: Biology

the DNA template has the following sequence 5' TGATC 3'. When depurination occurs what sequence would...

the DNA template has the following sequence 5' TGATC 3'. When depurination occurs what sequence would occur in the daughter strand of the altered strand?

a. 3' ACTA 5'
b. 3' ACTAA 5'
c. 3' ACTAG 5'
d. 3' AAG 5'

Solutions

Expert Solution

If the DNA template has the following sequence 5' TGATC 3'. When depurination occurs the sequence that would occur in the daughter strand of the altered strand is (d) 3' AAG 5'
The given sequence of template is 5'TGATC 3'
In depurination the purines Adenine (A) and Guanine (G) are removed. The daughter sequence being in 3' to 5' sequence forms from the parent sequence.
TEMPLATE 5'TGATC 3'
DEPURINATION 5' TTC 3'
DAUGHTER 3' AAG 5'
DNA is under constant repair due to UV radiation, chemicals causing mutations, and errors occured due to DNA replication. These various damages cause the DNA dimerizaton process to depurination. Depurinaion involves the removal of Purine bases from the DNA sequence. This takes place by hydrolysing the covalent bond between Purine Base and deoxyribose sugar and releases the purine base from the sequence. This results in the mutations in further process of DNA replication.


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