17. Size and charge dictate if a chemical will be filtered through the glomerulus in Bowman’s...

17. Size and charge dictate if a chemical will be filtered through the glomerulus in Bowman’s capsule.

Expert Solution

The components of blood must pass through the nephron tubules and surrounding blood-filled capillaries for purification. The channel is made up of phospholipid-bilayer membrane with embedded proteins. This layer is not permeable to polar molecules because the interior lipid region of the membrane is nonpolar and in order to cross through the nephron tubules, the membranes must have specialized channels

The embedded proteins of phospholipid-bilayer membrane is of cylindrical shape and is exposed to -

a) Hydrophobic surface amino acid residues on the outer side interacting with the non-polar tails of phospholipids in the bilayer

b) And a hydrophilic internal core residue that forms tunnel to pass on allows ions and polar molecule. Size of tunnel determines the size of particles passing through it

Thus, It is true that size and charge along with polarity of the channel dictate if a chemical will be filtered through the glomerulus in Bowman’s capsule.

gladiator answered 2 years ago

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