Question

Malaria is a mosquito-borne disease caused by parasites of the obligate intracellular Apicomplexa family, the most deadly of which, Plasmodium falciparum, prevails in Africa. Malaria imposes a huge health burden on the world’s most vulnerable populations, claiming the lives of nearly a million children and pregnant women each year in Africa alone. Although there is keen interest in eradicating malaria, we do not yet have the necessary tools to meet this challenge, including an effective malaria vaccine and adequate vector control strategies. Here we review what is known about the mechanisms at play in immune resistance to malaria in both the human and mosquito hosts at each step in the parasite’s complex life cycle with a view towards developing the tools that will contribute to the prevention of disease and death and ultimately the goal of malaria eradication. In so doing we hope to inspire immunologists to participate in defeating this devastating disease.

what are the main points

Answer 1

Main points :

• Malaria is deadly disease.
• It is caused by parasite , Plasmodium flaciparum.
• It is highly prevalent in Africa claiming many lives of pregnant women and children.
• There are not much vector control strategies due to complex life cycle of Plasmodium flaciparum.
• Also, there is no available vaccine to prevent malaria.
• Eradication of malaria aims at developing the tools that aims at prevention and control of malaria.
• Immunologists should work towards development of vaccine and breaking the chain to eradicate malaria.

These were the main points and summary to the above paragraph.

Hope this helps ! Thank you.