Question

What type of mutation would occur from a single nucleotide deletion (point mutation) within the coding sequence of a protein-coding gene?

a. a frameshift mutation

b. a silent point mutation

c. a nonsense point mutation

d. a missense point mutation

e. All of the choices are possible.

Answer 1

What type of mutation would occur from a single nucleotide deletion (point mutation) within the coding sequence of a protein-coding gene?

e. All of the choices are possible.

Explanation- Point mutation is a mutation in the single base pair of the coding sequence. It can be of the following types:

Frameshift mutations- occurs by addition or deletion of a base pair within the protein coding portion of a gene which has the effect of shifting the translational reading frame.

Silent mutation- type of point mutation without efferent phenotype. It occurs when the mutation in the new codon specifying the same amino acid has the unmutated codon.

Nonsense mutation- type of point mutation that changes a codon in a gene to one of the three termination codon.

Missense mutation- type of point mutation that alters the codon so that it specifies a different amino acid.

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